… part in the message-address concept, but its affinity for the κ receptor was not high. To improve
affinity, we synthesized five pentacyclic propellane derivatives … -bridged derivatives SYK-…

… and synthesis of the novel KOR selective pentacyclic derivatives … propellane derivatives,
which would make it easy to compare the position between morphinan and propellane skeletons…

… Herein, we report an attempt to design and synthesize novel KOR … Synthesis of new opioid
derivatives with a propellane skeleton and their pharmacologies: Part 5, novel pentacyclic …

… Aside from position 14 of the morphinan skeleton, the N-substituent also plays an important
role in opioid activities and, thus, new … Pentacyclic propellane derivatives were designed and …

… as its 4-bromobenzoylated derivative. Different from the parent hasubanan alkaloids, this
pentacyclic alkaloid contains an aza[4.3.3]propellane … [4.3.3]propellane skeleton. (16) Based on …

… and regioselective synthesis of oxo-thioxo[3.3.3]propellanes by one-pot three-… new
bonds in a single operation, which makes it an attractive method for the synthesis of [3.3.3]propellane …

… propellane derivative 56 by oxidative coupling in excellent … to rearrangement to form
new skeletons in a manner … this structure to provide the pentacyclic morphine core would …

… on a structurally homogeneous skeleton, differing only in the … the [4.3.1]propellane ring
system. Biogenetically these … , the stereoselective synthesis of these bicyclic skeletons has …